Organic Electronic Device
The recent development of optoelectronics and neural photosensitization tools, such as channelrhodopsin-2 (ChR2), voltage sensitive dyes and fusion proteins, offers new opportunities for non-invasive, cell-specific neuronal stimulation.
OLIMPIA technical goal is to develop highly efficient/effective organic optoelectronic devices able to provide optoelectronic stimulation, manipulation and read-out of bioelectrical activity of neurons and glial cells in vitro and in vivo.
Organic Optoelectronics has the characteristics required for the development of innovative biomedical tools for neuroscience fundamental investigations and applications.
The fundamental electronic and photophysical properties of organic materials make them suitable for the development of both photodetectors (OPD) and light sources (OLS) for neuroscience.
Optically pumped organic semiconductor lasers (OSLs) are among the most efficient mechanically flexible and spectrally tunable laser sources.
Voltage driven Organic Light emitting Diodes (OLEDs) are developed to a level that are now commercially available in small area active matrix displays (ICL), while organic light-emitting transistors (OLETs) are fully planar device structures that OLIMPIA partners have recently demonstrated to be an efficient alternative to OLEDs in terms of external quantum efficiency and micrometer spatial control of the light generation zone (ETC).
Compared with conventional photodetectors, OPDs display higher sensitivity, wider dynamic range, broader spectral range and better responsivity, which are important properties for devices to be interfaced with neural systems, where fast, yet limited, changes in spectral properties of voltage sensitive dyes are common.
OFET (ETC, CNR) and polymer based OECT (EMSE), also offer a unique opportunity to go beyond the current state-of-the art in terms of recording and manipulating signals from neural cells with high signal-to-noise ratio, flexibility, lower invasiveness and higher biocompatibility